Extrait

Background and study aims Urinary tract infections (UTIs) are common infections that can affect the bladder, the kidneys and the tubes connected to them. The aim of this study is to assess a new way of treating UTIs that involves a Point Of Care Test (POCT). The POCT aims to provide clinicians at the point of care (i.e. within the practice) within 24 hours with a diagnosis of bacterial UTI (or not) and information about whether the UTI is resistant to commonly used antibiotics. This study will determine whether using this POCT results in patients taking antibiotics correctly. The effect of using the POCT will also be assessed on antibiotic use, recovery (duration of symptoms and symptom burden), antibiotic resistance, UTI recurrence, hospitalisation, costs, and cost effectiveness. Who can participate? Non-pregnant women aged 18 and over with symptoms of a UTI What does the study involve? Participants are randomly allocated into two groups. One group receive standard care. The other group have their treatment guided by the POCT test. Participants in the POCT group are asked to provide urine and stool samples at the start of the study and two weeks later, with the urine sample being divided so that half is used for the POCT test and half is sent to be tested in a laboratory. Participants in both groups are asked to fill out a symptom diary each day for 14 days and their medical records are searched for information relevant to UTIs after 3 months. Cost data is also collected. What are the possible benefits and risks of patients? Patients are followed up closely by the research team, and provide data that may improve the quality of care for this common infection. Apart from the time and effort taken to provide data and samples, there are few risks to participants. Where is the study run from? The study is carried out in primary care research networks in Wales, England, Netherlands and Spain When is the study starting and how long is it expected to run for? June 2013 to July 2014 Who is funding the study? Seventh Framework Programme Who is the main contact? Nigel Kirby [email protected]

Critère d'inclusion

• Topic: Primary Care Research Network for England; Subtopic: Not Assigned; Disease: All Diseases

Liens

• ictrp
• isrctn