Femme et Homme
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Extrait
The main research question is to evaluate the effect of Calcitriol treatment as compared to placebo on left ventricular mass in patients with type 2 diabetes, left ventricular hyperthrophy and chronic kidney disease. Left ventricular hypertrophy is a marker and predictor of cardiovascular disease risk. Left ventricular mass will be assessed by magnetic resonance imaging. Interventions that reduce left ventricular hypertrophy may prevent cardiovascular disease. Currently it is not known if treatment with Calcitriol can affect left ventricular mass in patients with diabetes, left ventricular hypertrophy and kidney disease. We wish to study the effect of Calcitriol or placebo as add on treatment to existing medical treatments on left ventricular mass in a placebo controlled double blind study. Patients will continue with other medical treatments for their diabetes and kidney disease.
Critère d'inclusion
- Left ventricular hypertrophy, type 2 diabetes, chronic kidney disease