Extrait

In patients with Marfan syndrome:  oral beta-blockade (atenolol) does not reduce central aortic stiffness or pressure  ACE inhibition (perindopril) reduces central arterial pressure and improves aortic compliance  a non-dihydropyridine calcium antagonist (verapamil) reduces rate of rise of arterial pressure, aortic stiffness, and central arterial pressure  genotype affects the response to treatment

Critère d'inclusion

• Marfan Syndrome

Liens

• ictrp
• euctr