Essential Hypertension Clinical Trials

291 clinical trials for Essential Hypertension across international registries, including 11 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• Safety and Efficacy of Remote Ischemic Conditioning Treatment for Community-based Essential Hypertension — RECRUITING · NA
• Childhood-Onset Essential Hypertension Natural History Study — RECRUITING
• Safety and Pharmacokinetics Study of BCD101 in Healthy Volunteers — RECRUITING · PHASE1
• Phase 3 Trial to Evaluate the Efficacy and Safety of CKD-202A — RECRUITING · PHASE3
• To Evaluate the Safety and Efficacy of a Single-Use IVUS Ablation for Primary Hypertension — RECRUITING · NA
• Safety and Efficacy of Modulated Ultrasound Renal Denervation for HTN（FIM） — RECRUITING · NA
• A Phase III Clinical Study of Valsartan Oral Solution for the Treatment of Hypertension in Children and Adolescents — RECRUITING · PHASE3
• A Study to Evaluate the Efficacy and Safety of Co-administration of AD-227A and AD-227B — RECRUITING · PHASE3
• Effects of Remote Ischemic Conditioning on Blood Pressure in Older Patients With Hypertension — RECRUITING · NA
• Superselective Adrenal Arterial Embolization for Refractory Hypertension: A Proof-of-Concept Study — RECRUITING · NA
• Study of Bisoprolol (Nerkardou - Nerhadou International) 5 and 10 mg Oral Dissolvable Film (ODF) Treatment in Egyptian Patients With Essential Hypertension — RECRUITING · PHASE4
• A randomised, double-blind, parallel group study evaluating the efficacy and safety of co administration of triple combinations of olmesartan medoxomil, amlodipine besylate, and hydrochlorothiazide compared with the corresponding olmesartan- amlodipine combination in subjects with hypertension — COMPLETED · PHASE3
• A randomized, 32 week double-blind, parallel-group, multicenter study to compare the efficacy and safety of initiating treatment with combination (aliskiren/amlodipine) therapy in comparison with the sequential add-on treatment strategies in patients with essential hypertension. — COMPLETED · PHASE3
• A clinical trial on the interaction between aliskiren and furosemide in patients with heart failure. — COMPLETED · PHASE2
• A Study to Compare the Effect of Eprosartan versus Eprosartan Mesylate on Blood Pressure in Subjects with High Blood Presure — COMPLETED · PHASE3
• An international multicentre, randomized, parallel group, double-blind trial to evaluate different dose combinations of lercanidipine and enalapril in comparison with each component administered alone and with placebo in patients with essential hypertension. — COMPLETED · PHASE2
• A randomized, eight-week double-blind, parallel-group, multicenter study to evaluate the efficacy and safety of the combination of aliskiren / amlodipine (300/5 mg and 300/10 mg) in comparison with aliskiren 300 mg in patients with essential hypertension not adequately responsive to aliskiren 300 mg monotherapy. — COMPLETED · PHASE3
• A multicenter, double-blind, randomized study comparing the efficacy of combination therapy of Eprosartan respectively Ramipril with low-dose Hydrochlorothiazide and Moxonidine on blood pressure levels in patients with hypertension and associated diabetes mellitus type 2 (ASTRID – Antihypertensive treatment of Systolic/diastolic hypertension comparing Teveten and Ramipril in type 2 Diabetics). — ACTIVE_NOT_RECRUITING · PHASE3
• Direct renin inhibitor (aliskiren)and carotid plaques instability markers in hypertensive patients requiring carotid endoarterectomy — SUSPENDED · PHASE2
• An 8 week double-blind, multicenter, randomized, multifactorial, placebo-controlled, parallel-group study to evaluate the efficacy and safety of aliskiren administered alone and in combination with hydrochlorothiazide in patiens with essential hypertension — COMPLETED · PHASE2
• An open-label, multicenter study to evaluate the efficacy and tolerability of a 4 week therapy with the fixed dose combination of amlodipine 10 mg plus valsartan 160 mg in hypertensive patients not adequately responding to a 4 week therapy with the free combination of an angiotensin receptor blocker (olmesartan 20 mg) plus amlodipine 10 mg — COMPLETED · PHASE3
• A study conducted in several countries and centres to compare the efficacy and safety of an 8 week treatment of patients with high blood pressure with aliskiren 300mg given once daily in fasted state compared to fed state — COMPLETED · PHASE4
• Phase IV prospective, randomized, open with blind endpoints, parallel group study to evaluate the effect of Aliskiren on endothelial dysfunction in patients with essential hypertension — COMPLETED · PHASE4
• The study is a global phase-3 randomized study, with a double-blind treatment period of 8 weeks. — COMPLETED · PHASE3
• An eight-week randomised, 3-arm, double-blind study to compare the safety and efficacy of the combination of telmisartan 40mg + amlodipine 10mg versus telmisartan 80mg + amlodipine 10mg versus amlodipine 10mg monotherapy in patients with hypertension who fail to respond adequately to treatment with amlodipine 10mg monotherapy. — COMPLETED · PHASE3
• An eight-week double-blind, multi-center, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of aliskiren 75mg, 150mg and 300mg in elderly patients with essential hypertension when given with a light meal — COMPLETED · PHASE3
• Estudio aleatorizado, doble ciego, de grupos paralelos, multicéntrico, para comparar la eficacia y seguridad de aliskiren 300 mg administrado una vez al día y de aliskiren 150 mg administrado dos veces al día en pacientes con hipertensión esencial — COMPLETED · PHASE4
• An 8-week study to evaluate the efficacy (blood pressure lowering effect) and safety of LCZ696 given alone and in combination with amlodipine — COMPLETED · PHASE3
• EARLY METABOLIC CHANGES WITH THIAZIDE OR BETA BLOCKER THERAPY FOR ESSENTIAL HYPERTENSION (MAIN STUDY). — COMPLETED · PHASE4
• A multicenter, double-blind, randomized, parallel-group study to evaluate the safety, tolerability, and efficacy of once daily amlodipine/valsartan 5/80 mg as compared to amlodipine/valsartan 5/40 mg or to amlodipine 5 mg once daily in elderly patients with essential hypertension not adequately controlled after four weeks on amlodipine 5 mg once daily — COMPLETED · PHASE3
• Effectiveness of Entresto (Sacubitril/Valsartan) in Japanese Patients With Hypertension — COMPLETED
• Assess Sacubitril/Allisartan and Amlodipine in Patients With Essential Hypertension Uncontrolled With Sacubitril/Allisartan — COMPLETED · PHASE3
• Assess Sacubitril/Allisartan and Amlodipine in Patients With Essential Hypertension Uncontrolled With Amlodipine — COMPLETED · PHASE3
• A Phase II Clinical Study of QR12000 Compound Tablets in Patients With Moderate to Severe Essential Hypertension — COMPLETED · PHASE2
• To Evaluate the Renal Protective Effects and Safety of 'Fimasartan and Atorvastatin' or 'Fimasartan, Atorvastatin and Ezetimibe'. — NOT_YET_RECRUITING
• Phase III Study to Evaluate the Efficacy and Safety of AGSAVI in Patients With Essential Hypertension Inadequately Controlled With AGLS — COMPLETED · PHASE3
• Safety and Efficacy Evaluation of Non-invasive Temporal Interference Stimulation for Blood Pressure Modulation in Patients With Mild Essential Hypertension — NOT_YET_RECRUITING · NA
• Efficacy and Safety of DWC202404 and DWC202314 in Patients With Hypertension — COMPLETED · PHASE3
• Vascular Impact of Omega-3 in Metabolic Syndrome — COMPLETED · NA
• A Phase III Study to Efficacy and Safety of DWC202405/DWC202313 and DWC202314 in Patients With Hypertension — COMPLETED · PHASE3
• Heat Therapy in Older Hypertensive Women — COMPLETED · NA
• Effects of Antihypertensive Drug Treatment on Brain Blood Flow, Cognition, and Regulation of Nervous System in Older Adults With Hypertension. — COMPLETED · PHASE1
• Mat Pilates With Paced Breathing Versus Diaphragmatic Breathing in Stage II Hypertension — COMPLETED · NA
• REMIDEP-HTA Program for Hypertension Remission and Medication Deprescription — NOT_YET_RECRUITING · NA
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015-A and Co-administration of BR1015-3 and BR1015-2 Under Fed Conditions — NOT_YET_RECRUITING · PHASE1
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015-A and Co-administration of BR1015-1 and BR1015-2 Under Fasting Conditions — NOT_YET_RECRUITING · PHASE1
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015-A and Co-administration of BR1015-3 and BR1015-2 Under Fasting Conditions — NOT_YET_RECRUITING · PHASE1
• A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015-A and Co-administration of BR1015-1 and BR1015-2 Under Fed Conditions — NOT_YET_RECRUITING · PHASE1
• Study to Evaluate the Efficacy and Safety of TEL/AML/CTD in Elderly Patients With Essential Hypertension — ACTIVE_NOT_RECRUITING · PHASE4
• Specificity of Elevated Plasma EM66 Levels in Pheochromocytoma — COMPLETED · NA

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