Hypercholesterolemia Clinical Trials

873 clinical trials for Hypercholesterolemia across international registries, including 29 currently recruiting participants. Compare status, phase, eligibility criteria and locations.

• A Study to See How Safe and Effective Alirocumab is When Given Weekly to Adult Participants Who Have Hypercholesterolemia — RECRUITING · PHASE2
• Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia — RECRUITING · PHASE1
• Causes and Natural History of Dyslipidemias — RECRUITING
• A Post-Marketing Clinical Trial of Pemafibrate in Patients ｗith Hypercholesterolemia and Inadequate Response to Statins — RECRUITING · PHASE4
• Moderate-Intensity Statin Plus Ezetimibe in CKD and ASCVD — RECRUITING · NA
• A Study Of SHR-1918 In Participants With Hypercholesterolemia With Inadequate Lipid Control on Statins Plus PCSK9 Inhibitors — RECRUITING · PHASE2
• Dual PCSK9 Inhibition With Inclisiran and Alirocumab in Secondary Prevention — RECRUITING · PHASE4
• Improving Lipid Optimization Quality and Treatment Options in ASCVD — RECRUITING · NA
• Assessing the Effects of Corn and Avocado Oils on the Cardiometabolic Risk Factor Profile — RECRUITING · NA
• Pharmacogenomic Informed Statin Prescribing — RECRUITING · NA
• Long-term Follow-up of Participants Dosed With an Investigational Gene Editing Therapy for Cardiovascular Disease — RECRUITING
• Emergency Medicine Cardiovascular Risk Assessment for Lipid Disorders Trial — RECRUITING · PHASE2
• Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Bempedoic Acid in Italy — RECRUITING
• Multicenter Study on the Evaluation of Adherence, Persistence and Efficacy of Treatment With Inclisiran in Italy — RECRUITING
• Evaluation of Adherence, Persistence and Efficacy of Treatment With PCSK9 Inhibitors in Italy — RECRUITING
• Effect of Two Food Supplements on Lipid Profile in Patients With Mild Hypercholesterolemia — RECRUITING · NA
• Guideline Oriented Approach To Lipid Lowering In Asia-Pacific — RECRUITING · NA
• A Study to Evaluate the Effectiveness and Safety of Fixed-Dose Combination of Pitavastatin/ Ezetimibe — RECRUITING
• A Study on Evaluating the Safety of HST101 in Healthy Chinese Participants — RECRUITING · PHASE1
• PMMHRI-Pitavastatin Registry — RECRUITING
• Functional Cereal Products and Contribution to the Regulation of Metabolism and Obesity-induced Chronic Low-grade Inflammation. — RECRUITING · NA
• A Study on Efficacy and Safety of HST101 in Chinese Patients with Hypercholesterolemia — RECRUITING · PHASE3
• A PHASE 3, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE SAFETY AND EFFICACY OF MK-0616 IN ADULTS WITH HYPERCHOLESTEROLEMIA — RECRUITING · PHASE3
• Evaluation of a Digiphysical Screening Method to Identify and Diagnose Familial Hypercholesterolemia — RECRUITING
• Effect of food supplements with artichoke leaf extract and lactobacilli on LDL-cholesterol levels in subjects with LDL hypercholesterolemia — RECRUITING
• Alirocumab in Patients on a Stable Dialysis Regimen — RECRUITING · PHASE3
• "A MULTI-COUNTRY, MULTICENTER, SINGLE-ARM, OPEN-LABEL STUDY TO DOCUMENT THE SAFETY, TOLERABLITY AND EFFECT OF ALIROCUMAB ON ATHEROGENIC LIPOPROTEINS IN HIGH CARDIO-VASCULAR RISK PATIENTS WITH SEVERE HYPERCHOLESTEROLEMIA NOT ADEQUATELY CONTROLLED WITH CONVENTIONAL LIPID-MODIFYING THERAPIES." — RECRUITING
• A DOUBLE-BLIND, RANDOMIZED, MULTICENTER STUDY TO EVALUATE THE SAFETY AND EFFICACY OF AMG 145, COMPARED WITH EZETIMIBE, IN HYPERCHOLESTEROLEMIC SUBJECTS UNABLE TO TOLERATE AN EFFECTIVE DOSE OF A HMG-COA REDUCTASE INHIBITOR DUE TO MUSCLE RELATED SIDE EFFECTS — RECRUITING
• "A MULTI-CENTER, RANDOMIZED STUDY IN SUBJECTS WITH PRIMARY HYPERCHOLESTEROLEMIA OR MIXED DYSLIPDEMIA TO ASSESS SUBJECTS' ABILITY TO ADMINISTER A FULL DOSE OF AMG 145 IN HOME-USE, USING EITHER A 3.5ML PERSONAL INJECTOR OR A PREFILLED AUTOINJECTOR/PEN." — RECRUITING
• Additiv kolesterolsænkende effekt ved kombinationsbehandling med psyllium frøskaller og sojaproteinisolat i tillæg til hjerterigtig kost hos hyperkolesterolæmipatienter — COMPLETED · PHASE4
• Exploratory, double blind placebo controlled, randomized, single cross-over study to evaluate the potential anti-oxidant action of Niaspan — TERMINATED · PHASE2
• An Open-Label, Multicenter Study to Assess the Efficacy of Switching to a Combination tablet Ezetimibe/Simvastatin 10mg/40mg, Compared to Doubling the Dose of Statin in Patients Hospitalized With a Coronary Event — COMPLETED · PHASE3
• "A Multicenter, Randomized, Double-Blind, Parallel Arm, 6-Week Study to Evaluate the Efficacy and Safety of Ezetimibe/Simvastatin Versus Atorvastatin in Patients with Metabolic Syndrome and Hypercholesterolemia at High Risk for Coronary Heart Disease." — COMPLETED · PHASE4
• A Multicenter, Randomized, Double-Blind, Titration Study to Evaluate and Compare the Efficacy and Safety of Ezetimibe 10 mg Added on to Rosuvastatin 5 mg, 10 mg, 20 mg, or 40 mg Versus Up-Titration Rosuvastatin 10 mg, 20 mg, or 40 mg in Hypercholesterolemic Patients at Moderately High and High Risk for Coronary Heart Disease — COMPLETED · PHASE3
• A Phase II, Placebo-Controlled, Double-Blind, Randomised, 10-Week, Parallel-group Study to Assess the Efficacy of Different Doses of KB2115 as add on to Ezetimibe treatment in Patients with Primary Hypercholesterolemia — COMPLETED · PHASE2
• Study of the effects of blocking the enzyme PCSK9 on artery wall inflamation — COMPLETED · PHASE2
• Lipoprotein Metabolism in Normal Volunteers and Patients With High Levels of Lipoproteins — COMPLETED
• A Multiple Ascending Dose Study of HTD1801 in Adults With Hypercholesterolemia — COMPLETED · PHASE1
• A Study of Bempedoic Acid/Ezetimibe/High-intensity Statin in Patients Without Cardiovascular Events — NOT_YET_RECRUITING · PHASE3
• A Study of Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-013) CORALreef Lipids — COMPLETED · PHASE3
• Alleviation of Hypercholesterolemia Through Newly Developed Cookies Supplementedwithpumpkin (Cucurbita Pepo L.) Seeds and Walnuts (Juglans Regia L.) Among Arthrosclerosispatients. — COMPLETED · NA
• RCT for the Chinese Medicine in Treating Hypercholesterolemia — NOT_YET_RECRUITING · PHASE2
• A Study to Investigate LDL-cholesterol Lowering With Inclisiran Compared to Bempedoic Acid in Patients With Atherosclerotic Cardiovascular Disease. — COMPLETED · PHASE4
• A PHASE III RANDOMISED, DOUBLE-BLIND, PARALLEL-GROUP STUDY TO ASSESS THE EFFECT OF FIXED DOSE COMBINATION LAROPROVSTAT/ROSUVASTATIN COMPARED WITH ROSUVASTATIN ON LOW-DENSITY LIPOPROTEIN CHOLESTEROL IN PATIENTS WITH HYPERCHOLESTEROLAEMIA — NOT_YET_RECRUITING · PHASE3
• A Clinical Study in Children With Heterozygous Familial Hypercholesterolemia (HeFH) Aged 6 to 17 Treated Once Daily With Bempedoic Acid Oral Dosing (CLEAR Path 1) — COMPLETED · PHASE2
• A PHASE III RANDOMISED, DOUBLE-BLIND, FACTORIAL DESIGN STUDY TO ASSESS THE EFFECT OF FIXED DOSE COMBINATION LAROPROVSTAT/ROSUVASTATIN COMPARED WITH LAROPROVSTAT, ROSUVASTATIN, AND PLACEBO ON LOW-DENSITY LIPOPROTEIN CHOLESTEROL — NOT_YET_RECRUITING · PHASE3
• A Phase 3, Open-label Extension Study to Evaluate the Safety and Efficacy of MK-0616 in Adults With Hypercholesterolemia — TERMINATED · PHASE3
• To Evaluate the Safety and Pharmacokinetic Characteristics of AJU-C716 and C716R in Healthy Adults — COMPLETED · PHASE1
• Assessing Outcomes of Enhanced Chronic Disease Care Through Patient Education and a Value-based Formulary Study — COMPLETED · NA
• Effects of a Digital Health Application (Lipodia) on LDL-cholesterol Levels — COMPLETED · NA

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