A national perioperative platform trial to improve outcomes for surgical patients (PROTECT)

Registry ID

ISRCTN14639555

Source registry

ISRCTN

Status

Recruiting

Study type

INTERVENTIONAL

Sponsor

Queen Mary University of London

Enrollment

1000

Start date

2026-03-06

Completion date

2035-02-01

Last update

2026-08-17

Conditions

• Surgery

Summary

All adult patients (≥18 years) being treated within a surgical care pathway at the recruitment sites will be eligible for the trial.

Detailed description

A common outcome dataset will be collected for all patients at 30 days and 90 days after surgery. In addition, longer-term outcomes may be collected using routinely collected data (for example Hospital Episode Statistics (HES) and Civil Registration data) up until the last follow up time-point for the participant according to the nature of the groups in which they are enrolled in. Where applicable, primary and secondary outcomes will be described in full in the relevant appendix. Additionally, for CTIMPs, depending on the risk and status of the investigations, part of the objectives will be to collect safety endpoints.

Interventions

• OTHER: A common outcome dataset will be collected for all patients at 30 days and 90 days after surgery. In addition, longer-term outcomes may be collected using routinely collected data (for example Hospital Episode Statistics (HES) and Civil Registration data) up until the last follow up time-point for the participant according to the nature of the groups in which they are enrolled in. Where applicable, primary and secondary outcomes will be described in full in the relevant appendix. Additionally, f

Inclusion criteria

All adult patients (≥18 years) being treated within a surgical care pathway at the recruitment sites will be eligible for the trial.

Exclusion criteria

Inability or refusal to provide informed consent.

Locations

• , , Scotland
• , , United Kingdom
• , , England
• , , Wales

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