High flow nasal oxygen for patients undergoing elective major abdominal surgery
Adult patients undergoing elective major abdominal surgery
The master protocol for this study is registered at https://www.isrctn.com/ISRCTN14639555 Eligible patients will be approached for consent before surgery. If consented their baseline and demographic information will be collected for study purposes. There are two groups a patient will be randomly allocated to after surgery, usual care or High Flow Nasal Oxygen (HFNO) administered for 4 hours post surgery, other information pertaining to the surgical procedure and follow up information at 30 days will also be collected to answer the research question.
1. Patients aged 50 years and over undergoing elective major abdominal surgery, using open, laparoscopic or robotic surgical technique
1. Inability or refusal to provide informed consent 2. Anticipated requirement for invasive or non-invasive respiratory support for at least 4 hours after surgery as part of routine clinical care 3. Previous enrolment in the PROTECT-HFNO comparison 4. Clinician refusal