A study to assess if a large-scale clinical trial giving colchicine to dialysis patients is feasible

Colchicine and dialysis patients; a feasibility study

Registry ID
ISRCTN91308625
Source registry
ISRCTN
Status
Recruiting
Study type
INTERVENTIONAL
Sponsor
King's College London
Enrollment
100
Start date
2025-04-01
Completion date
2027-11-01
Last update
2026-08-17

Conditions

Summary

Haemodialysis

Detailed description

Colchicine 0.5 mg once daily orally will be given for 3 months and 2 weeks to all enrolled patients

Interventions

Inclusion criteria

1. Anyone who is undergoing haemodialysis 2. Aged 18 years or over 3. Able to give informed consent

Exclusion criteria

1. Already taking colchicine for a clinical indication. 2. Taking a drug known to increase colchicine levels. 3. Has a previously documented intolerance of or allergy to colchicine 4. Has a history of chronic liver disease, or abnormal liver function (i.e. ALT > 1.5 x upper limit of normal). Patients with a history of hepatitis are eligible provided these limits are not exceeded.

Locations

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