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Kusajili – Centralise les essais cliniques mondiaux
Résultat
de votre recherche par promoteur : IST. DI RICERCHE FARMACOLOG. M. NEGRI
Femme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
A PHASE II RANDOMIZED NON COMPARATIVE STUDY ON THE ACTIVITY OF TRABECTEDIN OR GEMCITABINE + DOCETAXEL IN METASTATIC OR LOCALLY RELAPSED UTERINE LEIOMYOSARCOMA PRETREATED WITH CONVENTIONAL CHEMOTHERAPY
Primary objective will be to assess the clinical benefit rate (defined as 6-month progression free rate) with T in patients with locally relapsed/metastatic uterine leiomyosarcoma pretreated with anth...
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unknown
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Femme et Homme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
A prospective, randomized, open label blinded end point probe trial to evaluate whether, at comparable blood pressure control, combined therapy with the ACE inhibitor Benazepril and the angiotensin II receptor blocker ARB Valsartan, reduces the incidence of microalbuminuria more effectively than Benazepril or Valsartan alone in hypertensive patients with type 2 diabetes and high-normal albuminuria VARIETY Study
To evaluate whether, at comparable blood pressure control, dual RAS blockade with combined therapy with halved doses of benazepril 10 mg/day and valsartan 160 mg/day reduces the incidence of micro...
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Femme et Homme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
Fatal familial insomnia: preventive treatment with doxycycline of at risk individuals Insonnia Fatale Familiare: trattamento preventivo con doxiciclina in soggetti a rischio
To prevent the FFI onset in subjects carrying the Prion D178N/129M Prevenire l'insorgenza della malattia FFI in soggetti portatori della mutazione Prion D178N/129M
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unknown
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Femme et Homme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
EFFECTS OF LONG-ACTING SOMATOSTATIN ON DISEASE PROGRESSION IN PATIENTS WITH AUTOSOMAL DOMINANT POLYCYSTIC KIDNEY DISEASE AND MODERATE/SEVERE RENAL INSUFFICIENCY(ALADIN II STUDY)
To compare the effect of long acting somatostatin analogue versus placebo on the total kidney volume (TKV) change (delta TKV) assessed by spiral computed tomography (spiral CT) after one year of treat...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
A PILOT STUDY TO EVALUATE THE INCIDENCE OF HYPONATREMIA IN A MEDICAL-SURGICAL HOSPITAL AND TO EXPLORE THE EFFICACY AND SAFETY OF TOLVAPTAN IN THE CLINICAL PRACTICE STUDIO PILOTA PER VALUTARE L'INCIDENZA DI IPONATREMIA NEI PAZIENTI OSPEDALIZZATI E PER ESPLORARE L'EFFICACIA E LA SICUREZZA DELL'IMPIEGO DI TOLVAPTAN NELLA PRATICA CLINICA
To compare between the two treatment arms: - the proportion of subjects achieving normonatremia (Serum sodium>135 mEq/L); - the absolute changes vs baseline in serum sodium levels considered as a c...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
A prospective, sequential study to assess the efficacy of rituximab therapy in maintaining remission of nephrotic syndrome after steroid and immunosuppressive therapy withdrawal in patients with steroid-dependant or multirelapsing minimal change disease or focal segmental glomerulosclerosis
The study is primarily aimed at evaluating whether Rituximab may maintain stable NS remission after tapering and withdrawal of steroid and immunosuppressive therapy in patients with MCD or FSGS and st...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
A prospective, randomized, double-blind, placebo controlled clinical trial to assess the effects of long-acting somatostatin (Octreotide LAR)therapy on disease progression in patients with Autosomal Dominant Polycystic Kidney Disease and moderate to severe renal insufficiency Studio per valutare l'effetto a lungo termine di un analogo della somatostatina(Octreotide LAR) in pazienti affetti da malattia policistica del rene e insufficienza renale cronica di grado moderato/severo
Short-term (1-year) To compare the effect of long acting somatostatin analogue versus placebo on total kidney volume (TKV) change (delta TKV) as assessed by spiral computed tomography (spiral CT) sca...
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Femme et Homme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
Clinical study of the association between n-3 PUFA and statin effects on inflammation and lipids
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
GiSAS trial aripiprazole, olanzapine and haloperidol in the long term treatment of schizophrenia
To evaluate the onset of metabolic syndrome over a 12-months period in patients with schizophrenia treated with aripiprazole, olanzapine and haloperidol.
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Femme et Homme Max 99 ans
IST. DI RICERCHE FARMACOLOG. M. NEGRI
MAJ Il y a 4 ans
A PROSPECTIVE, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL TO EVALUATE THE EFFECT OF 6-MONTH ACETYLCARNITINE THERAPY ON ARTERIAL BLOOD PRESSURE, LIPID AND METABOLIC PROFILE, AND KIDNEY FUNCTION IN HYPERTENSIVE PATIENTS WITH TYPE 2 DIABETES ON BACKGROUND SIMVASTATIN THERAPY (DIABASI STUDY)
To asses the effect of 6-month therapy with acetylcarnitine compared to placebo on systolic blood pressure in 228 patients with type 2 diabetes, arterial hypertension and dyslipidemia on stable backgr...
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Essai clos aux inclusions
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