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Kusajili – Centralise les essais cliniques mondiaux
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de votre recherche par promoteur : GlaxoSmithKline
Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Ltd
MAJ Il y a 4 ans
Study evaluating safety and efficacy of mepolizumab in the treatment of COPD patients with frequent exacerbations
To evaluate the efficacy and safety of mepolizumab 100 mg subcutaneous (SC) given every 4 weeks compared to placebo on the frequency of moderate and severe exacerbations in COPD subjects at high risk...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Ltd
MAJ Il y a 4 ans
PM1116197 is a Clinical Study to Compare the Incidence of Major Adverse Cardiovascular Events in Subjects Presenting with Acute Coronary Syndrome Treated with Losmapimod Compared to Placebo 1. Losmapimod kezelés a p38 kináz, mint terápiás célpont gátlására és az akut koronária-betegséget követő kimenetel módosítására (LATITUDE)-TIMI 60 2. Egy új készítmény vizsgálata szívrohamon átesett betegek kezelésére
The primary objective is to evaluate the efficacy of oral losmapimod 7.5 mg BID compared to placebo when added to standard of care in subjects with ACS on the time to first occurrence of adjudicated M...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Biologicals
MAJ Il y a 4 ans
A phase II, controlled, randomized, single blind study to evaluate the immunogenicity, safety and reactogenicity of the low dose influenza vaccine adjuvanted with AS03 compared to Fluarix™ (GlaxoSmithKline Biologicals) administered intramuscularly in elderly 60 years and older
To assess the humoral immune response (anti-haemagglutinin) elicited by the low dose influenza vaccine adjuvanted with AS03 and by Fluarix, with the Northern Hemisphere 2006-2007 influenza vaccine com...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Biologicals
MAJ Il y a 4 ans
A phase IIIb, open, controlled study to assess the effect of prophylactic antipyretic treatment on the rate of febrile reactions following concomitant booster administration of GlaxoSmithKline (GSK) Biologicals’ 10-valent pneumococcal conjugate vaccine with GSK Biologicals’ Infanrix hexa vaccine in children at 12-15 months of age following a 3-dose primary vaccination in study 10PN-PD-DIT-010 (107017) and to evaluate the impact of pneumococcal vaccination on nasopharyngeal carriage compared to a pneumococcal vaccine unprimed control group receiving GSK iologicals' meningococcal serogroup ACWY conjugate vaccine
To determine the percentage reduction in febrile reactions (rectal temperature >=38.0°C or oral/axillary/tympanic >=37.5°C) when prophylactic antipyretic treatment is administered compared to no proph...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline AB
MAJ Il y a 4 ans
A Multicentre, Randomised, Double-Blind, Parallel Group, 24 Week Study to Compare the Effect of the Salmeterol/Fluticasone Propionate Combination Product (SERETIDE) 50/250mcg with Salmeterol 50mcg Both Delivered Twice Daily via the DISKUS/ACCUHALER Inhaler on Lung Function and Dyspnoea in Subjects With Chronic Obstructive Pulmonary Disease (COPD)
To compare the effectiveness of SERETIDE 50/250mcg with salmeterol 50mcg both delivered twice daily via the DISKUS/ACCUHALER inhaler on lung function (Trough FEV1) and relief of dyspnoea as measured ...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research and Development Ltd
MAJ Il y a 4 ans
A study of a new medicine, an intravenous antibiotic (GSK2251052) in adults, with complicated urinary tract infection or pyelonephritis
To evaluate the safety and tolerability of GSK2251052 in the treatment of adult subjects with lower cUTI and pyelonephritis (complicated and uncomplicated). To evaluate the clinical and microbiologic...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Ltd
MAJ Il y a 4 ans
A six week randomized, double-blind, multi-center, placebocontrolled, exploratory, adaptive design study to explore the antidepressant properties of the p38 MAP kinase inhibitor GW856553 compared to placebo in adult subjects with Major Depressive Disorder
To evaluate the clinical antidepressant effects of GW856553 versus placebo treatment at Week 6 in adult subjects diagnosed with MDD with symptoms of decreased energy and interest, and with psychomotor...
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Essai clos aux inclusions
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Femme et Homme Max 99 ans
GlaxoSmithKline Research & Development Ltd
MAJ Il y a 4 ans
Study in subjects with anemia of chronic kidney disease to assess safety and efficacy of daprodustat compared to darbepoetin alfa
•To compare daprodustat to darbepoetin alfa for cardiovascular (CV) safety (non-inferiority) •To compare daprodustat to darbepoetin alfa for hemoglobin (Hgb) efficacy (non-inferiority)
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Femme et Homme Max 99 ans
GlaxoSmithKline Biologicals
MAJ Il y a 4 ans
Safety and reactogenicity of GSK Biologicals’ DTPa-IPV/Hib (Infanrix-IPV/Hib) in infants
To assess the safety and reactogenicity of the study vaccine administered as a three-dose primary vaccination course.
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Femme et Homme Max 99 ans
GlaxoSmithKline Consumer Healthcare
MAJ Il y a 4 ans
A Proof-of-Principle Analgesic Adjuvant Pilot Study in Post-Operative Dental Pain
To compare the analgesic efficacy of theobromine + paracetamol versus paracetamol alone.
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unknown
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