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Kusajili – Clinical trials directory
Result
of your search per sponsor: Vertex Pharmaceuticals
Woman and Man Max 99 years
Vertex Pharmaceuticals Incorporated
Update Il y a 4 ans
A Phase 2 Rollover Protocol of Telaprevir (VX-950) in Combination with Peginterferon Alfa-2a (Pegasys®) and Ribavirin (Copegus®) in Subjects Enrolled in the Control Group (Group A) of Study VX06-950-106, VX05-950-104 and VX05-950-104EU Who did not Achieve or Maintain an Undetectable HCV RNA Level Through Sustained Viral Response
To provide access to a telaprevir-based treatment to subjects enrolled in the Peg IFN alfa-2a plus ribavirin Control Group (Group A) of Studies VX06 950-106 (Study 106), VX05-950-104 (Study 104) or VX...
Country
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organs
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Specialty
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Closed trial
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Woman and Man Max 99 years
Vertex Pharmaceuticals Incorporated
Update Il y a 4 ans
A study in children aged 6 Through 11 Years With Cystic Fibrosis to assess the efficacy and safety of a combination of two experimental drugs
To evaluate the efficacy of lumacaftor in combination with ivacaftor in subjects aged 6 Through 11 years with cystic fibrosis (CF) who are homozygous for the F508del mutation on the CF transmembrane c...
Country
None
organs
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Specialty
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Closed trial
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Woman and Man Max 99 years
Vertex Pharmaceuticals Incorporated
Update Il y a 4 ans
A Pilot Open-Label Study to Investigate the Safety and Anti-inflammatory Effects of VX-765, an Orally Administered Interleukin-1β Converting Enzyme Inhibitor, in Patients with Muckle-Wells Syndrome
Investigate safety/tolerability, anti-inflammatory effect and pharmacokinetics of VX-765 in patients with Muckle-Wells Syndrome.
Country
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organs
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Specialty
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unknown
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Woman and Man Max 99 years
Vertex Pharmaceuticals Incorporated
Update Il y a 4 ans
Rollover Study to Evaluate the Safety and Efficacy of Long-term Treatment with Lumacaftor in Combination with Ivacaftor
To evaluate the long term safety and tolerability of lumacaftor in combination with ivacaftor in subjects aged 6 years and older with cystic fibrosis (CF), homozygous for the F508del CFTR mutation, wh...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Vertex Pharmaceuticals Incorporated
Update Il y a 4 ans
Study of Ivacaftor in Subjects With Cystic Fibrosis Who Have the R117H-CFTR Mutation
To evaluate the efficacy of ivacaftor in subjects with cystic fibrosis (CF) who have the R117H-CF transmembrane conductance regulator (CFTR) mutation
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Vertex Pharmaceuticals Incorporated
Update Il y a 4 ans
A study to investigate the safety and effectiveness of telaprevir in combination with peginterferon alfa-2a and ribavirin in treating chronic hepatitis C virus infection in subjects who are co-infected with hepatitis C virus and immunodeficiency virus (HIV)
To assess the hepatitis C antiviral efficacy of telaprevir, peginterferon alfa-2a, and ribavirin
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Vertex Pharmaceuticals Inc
Update Il y a 4 ans
A Study to Evaluate the Safety and Efficacy of VX-371 in Subjects With Cystic Fibrosis Who Are Homozygous for the F508del-CFTR Mutation
To evaluate the safety and efficacy of treatment with VX-371 in hypertonic saline (HS) compared to HS alone in subjects with cystic fibrosis (CF) who are ≥12 years of age, homozygous for the F508del-C...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Vertex Pharmaceuticals Incorporated
Update Il y a 4 ans
A Magnetic Resonance Imaging Study and Arthroscopic Biopsy Substudy in Subjects With Active Rheumatoid Arthritis Receiving VX-509, an Oral JAK3 Inhibitor
• To evaluate the efficacy of VX 509 across a range of doses • To evaluate the early effect of VX 509 administration on joint structures as assessed by magnetic resonance imaging (MRI)
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
Vertex Pharmaceuticals Incorporated
Update Il y a 4 ans
A study in people with Cystic Fibrosis ( a rare hereditary pulmonary disease) to assess the efficacy and safety of a combination of two experimental drugs Estudio en personas con Fibrosis Quística (una rara enfermedad pulmonar hereditaria) para evaluar la eficacia y seguridad de la combinación de dos fármacos experimentales
To evaluate the efficacy of lumacaftor in combination with ivacaftor through Week 24 in subjects with Cystic Fibrosis who are homozygous for the F508del-CFTR mutation Evaluar la eficacia de luma...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Vertex Pharmaceuticals Incorporated
Update Il y a 4 ans
A Study to Evaluate the Efficacy and Safety of VX-765 in Subjects With Treatment-Resistant Partial Epilepsy
To evaluate the efficacy, safety, and tolerability of VX-765 to treat seizures in subjects with treatment resistant partial epilepsy
Country
None
organs
None
Specialty
None
Closed trial
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