A Phase IIa, two-center, randomized, double-blind study with parallel groups to evaluate the anti-mycotic and anti-inflammatory efficacy of topical combinational product LAS 41003 versus corresponding mono-substances in patients with inflammatory tinea pedis To assess the efficacy of a combined octenidine/prednicarbate cream in comparison to creams with prednicarbate or octenidine alone after once daily treatment over a 2-week period in patients with infl...

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Study on the efficacy of Verrumal(R) compared to placebo and Solaraze(R) in the treatment of actinic keratosis grade I to II Superiority to placebo and non-inferiority to Solaraze with respect to histological clearance of target lesion.

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A prospective comparator controlled randomized exploratory study on the efficacy of LAS 41005 compared to cryotherapy in subjects with hyperkeratotic actinic keratosis Efficacy and safety of LAS 41005 compared to cryotherapy in subjects with moderate to severe hyperkeratotic actinic keratosis (confirmed by punch biopsies).

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Randomized, observer-blind, multi-center, reference-controlled phase IIb study to evaluate the efficacy of topically applied LAS41002 lotion in the treatment of scalp psoriasis The primary objective of this study is the comparison of test product versus reference product. Test product should be non-inferior to reference product based on relative reduction from baseline in TS...

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A 12 day placebo- and reference-controlled, double-blind, single center, randomized, phase II clinical study with an intraindividual comparison, investigating the anti-psoriatic efficacy and the tolerability of LAS41002 lotion in a psoriasis plaque test The primary objective of this study is the clinical examination (visually and by palpating the respective test area) of the reduction of psoriatic lesions: LAS41002 lotion better than (superior to) pl...

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A phase II trial to evaluate the anti-psoriatic efficacy and tolerability of tazarotene in a gel formulation in patients with mild to moderate nail psoriasis - parallel group comparison The primary objective of this trial is to assess the anti-psoriatic efficacy and tolerability of tazarotene in a gel formulation in patients with mild to moderate nail psoriasis compared to the vehicl...

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Double-blind, randomized, multi-centre phase II study to evaluate the efficacy and safety of topically applied LAS41007 once daily and LAS41007 twice daily versus Solaraze® 3% gel twice daily in the treatment of actinic keratosis grade I to II The primary study objectives are to compare the efficacy of 5% diclofenac gel twice daily to Solaraze® 3% gel twice daily, assessed by histology (according to Röwert-Huber, 2007) to evaluate the clear...

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A phase IIa single-center, randomized, controlled, observer-blind study to investigate the antimicrobial efficacy of topical formulations containing octenidine and prednicarbate in an"expanded flora test" with healthy subjects Testing whether topical formulations containing Octenidine and Octenidine plus Prednicarbate exert an in vivo antibacterial action on skin surface bacteria multiplied by occlusion using the "expanded ...

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A phase II, single-center, randomized, controlled, observer-blind study to determine the non-inferiority of a topical mometasone formulation vs a marketed comparator by evaluation of the anti-psoriatic efficacy in a psoriasis plaque test To determine the non-inferiority of a new topical corticsteroid formulation vs the marketed product Ecural® Fettcreme in a psoriasis plaque test

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Efficacy and Safety of different formulations of LAS 41004 compared to active control and placebo The objective of the study is to gain an indication of efficacy for five distinct combinations of bexarotene and betamethasone dipropionate in different concentrations, and one combination of tazarote...

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