Octreotide PET/CT scan for the imaging of disease activity in neurologic and cardiac sarcoidosis • The main objective is to evaluate the role of 68Ga-DOTA-NOC PET/CT in the imaging of disease activity in suspected neurological and cardiac sarcoidosis.

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Local antibiotics in the treatment of wound infections after cardiac surgery Lokale antibiotica bij de behandeling van wondinfecties na openhartchirurgie The aim of our study is to evaluate clinical outcomes of patients primarily closed over Redon catheters for the treatment of post-sternotomy mediastinitis, comparing the application of local gentamici...

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An efficacy, safety and pharmacokinetic study on the short-term and long-term use of METFORMIN in obese children and adolescents The primary objective of the METFORMIN study is to determine the efficacy of metformin in combination with lifestyle-intervention in obese children and adolescents with insulin resistance versus place...

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A phase II study of isolated lung perfusion with melphalan followed by pulmonary metastatectomy in patients with resectable pulmonary metastases of colorectal carcinoma, soft tissue sarcoma and osteosarcoma To determine time to progression of the primary malignancy (locally advanced or metastatic) in patients treated with isolated lung perfusionwith mephalan followed by pulmonary metastatectomy.

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RITUXIMAB IN PROGRESSIVE LUNG INFLAMMATION Rituximab behandeling bij toenemende long ontsteking This project will address rare Immune mediated inflammatory diseases (IMIDs) involving the lungs. When left untreated, interstitial pneumonitis (IP) can lead to poor quality of life and increased mort...

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Reponse to vaccination in patients with bonemarrowcancer who are treated with chemotherapy. Respons op vaccinatie bij patienten met beenmergkanker die behandeld worden met chemotherapie To compare the number of responders to vaccination with the influenza virus vaccine and pneumococcal vaccine at different time points in treatment cycle of lenalidomide. Doel van het onderzoek ...

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Antiplatelet therapy for patients undergoing transcatheter aortic valve implantation Bloedverdunning bij patiënten die een aortaklepvervanging ondergaan 1. To investigate the safety and efficacy of omission of clopidogrel during follow-up in patients without an indication for oral anticoagulation (OAC) after TAVI (Cohort A); 2. To investigate the safe...

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Bloed transfusies na aorta chirurgie Blood transfusions after aorta surgery The primary objective of this study is, to answer the following question: Leads a primary coagulation corrected with a single dose of fibrinogen after (ascending) aorta arc correction to an equivalen...

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Dexamethasone infusion in community-acquired pneumonia Is there a significant reduction on length of hospital stay in patients with a CAP treated with intravenous dexamethasone?

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Infliximab dosing based on blood concentrations in patients with sarcoidosis: smart dosing Infliximab doseren op basis van concentraties in het bloed bij patiënten met sarcoidose: slimmer doseren To determine whether serum concentration guided dosing of infliximab is not inferior to standard dosing based on bodyweight in patients with severe sarcoidosis in terms of FVC change from baseline at ...

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