Vitamin K1 to slow vascular calcification in hemodialysis patients Vitamin K1 Gabe zur Verlangsamung der Gefäßverkalkung bei Hämodialysepatienten Attenuation of the progression of coronary and aortic calcification

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Neoadjuvant chemotherapy with Cabazitaxel in high risk prostate cancer patients prior to radical prostatectomy Neoadjuvante Chemotherapie mit Cabazitaxel vor der radikalen Prostatektomie The primary goal of this trial is to define the pathologic complete response rate of cabazitaxel chemotherapy in patients with untreated, high-risk localized prostate cancer.

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RUXOlitinib versus BEst Available Therapy in patients with high-risk polycythemia vera or high-risk essential thrombocythemia – The RUXO-BEAT Trial Ruxolitinib im Vergleich zur besten verfügbaren Therapie in Patienten mit Hoch-Risiko Polycythemia vera oder Hoch-Risiko Essentieller Thrombozythämie – Die RUXO-BEAT Studie The objective of the Ruxo-BEAT trial is to assess the feasibility, safety, and efficacy of administration of ruxolitinib vs. best available therapy in patients with high-risk PV or high-risk ET. Pri...

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Prospective, randomized study of the efficacy of photodynamic therapy in actinic keratosis Our preliminary experience with the Hydrosun-radiator (halogen lamp) indicates that photodynamic therapy (PDT) with visible light (VIS) and water-filtered infrared A (wIRA) compared to conventional l...

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Administration of Rifaximin to improve liver regeneration and function after liver resection Anwendung von Rifaximin nach Leberresektion zur Verbesserung der Leberregeneration und Organfunktion to examine the effect of Rifaximin on postoperative liver function in patients with malignant liver disease requiring major liver resection

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Comparison of Marcumar and ASS as to Progression of Heart Valve Calcification Vergleich von Marcumar und ASS hinsichtlich des Fortschreiten der Herzklappen-Verkalkung The objective of the study is the comparison of coronary and valvular progression of calcification in the multi-slice CT at patients with Phenprocoumon therapy versus patients with ASS therapy. Theref...

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Pharmakotherapie kognitiver Defizite bei schizophrenen Störungen – Randomisierte placebokontrollierte Doppelblindstudie mit Pergolid versus Tolcapon TOCTAP (Treatment of Cognitive Deficits in Schizophrenia with Tolcapone and Pergolide) Verbesserung präfrontaler kognitiver Funktionen bei Patienten mit schizophrenen Störungen. Hauptzielparameter ist die Veränderung des MCCB nach 6 Wochen gegenüber dem Vor-wert.

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Emergence times and airway reactions in general laryngeal mask airway anesthesia Dauer der Aufwachphase und Zustand der Atemwege nach der Vollnarkose mit der Kehlkopfmaske (Larynxmaske) The aim of this study is first to assess if desflurane is superior in order to achieve a faster emergence from anesthesia (stating the date of birth). a

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Effect of Empagliflozin on Systemic Vascular Resistance and Cardiac Output in Patients with Type 2 Diabetes Wirkung von Empagliflozin auf systematische Gefäßwiderstand und das Herzzeitvolumen bei Patienten mit Diabetes Mellitus (Typ 2) Effect of empagliflozin 10 mg once daily on cardiac output in comparison to placebo after 1 day, 3 days and 12 weeks of treatment (measured with a noninvasive monitoring [ClearSight System]). Di...

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Perioperative chemotherapy with FOLFOX plus Cetuximab versus adjuvant FOLFOX plus Cetuximab for patients with resectable liver metastases of colorectal carcinoma The first primary objective of the study is to compare the postoperative complication rate according to Clavien score (> grade 1) of a perioperative chemotherapy with a postoperative regimen. A secon...

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