Enhancement by tacrolimus of nerve regeneration after peripheral nerve repair The aim of this study is to evaluate in humans a potential benefit related to Tacrolimus after nerve repair. This is a open, prove of concept type of study, where the speed and quality of nerve regene...

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Etude des effets d'un antagoniste calcique(la barnidipine) sur la sensibilité des chémorécepteurs et l'activité orthosympathique study the effects of ca channel blockers on the chemoreflex and sympathetic activity

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Fertility preservation in breast cancer patients: oocytes or embryos vitrification. Préservation de la fertilité chez les patientes atteintes de cancer du sein : vitrification des ovocytes ou des embryons The aim of this study is to evaluate the feasibility of gonadotropins ovarian stimulation associated with Letrozole before chemotherapy in breast cancer patients in order to preserve their fertility.

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Effect of Voluven on postoperative morbidity after gynaecological surgery To evaluate the incidence of postoperative nausea and vomiting after gynaecological surgery

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optimization of doses of broad spectrum B-lactames (ceftazidim and meropenem) and vancomycin in septic patient traeted with chronic hemodialysis interventional study of the pharmacocinetics of ceftazidim, meropenem and vancomycin in chronic hemodialysis patients tank to establish recommandations for doses of this antibiotics based on the evide...

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A prospective placebo controlled study of botulilium toxin (BOTOX) on gait disorder induced by spastic equinovarus foot The main objective is to assess the analytical and functional effects of Botox injected into the muscles of the calf on patients with gait impairment due to spastic equinus foot.

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Comparison of the efficacy of pneumococcal and tetanus vaccination between hemodialysis patients and renal tranpslant recipients treated with Mycophenolic acid(VACC-IR) study To compare renal transplant reicipients and dialyzed patients for the proportion developing an antibocy response to 23-valent pneumococcal polysaccharid vaccine

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GLP-1 analogs for Freidreich's Ataxia treatment In this pilot sudy our aim is to assess the frataxin-inducing effects of exenatide and liraglutide in FRDA patients. Safety and tolerability of 5 weeks treatment with exenatide and liraglutide in pati...

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Impact of 25-hydroxy vitamin D deficiency and its correction on mineral and bone disorde among hemodialysis patients •To assess the percentage of patients with appropriate control plasma levels of calcium, phosphorus, calcium x phosphorus product and intact parathormone following correction of the 25-OH vitamin D by...

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Colistin dosage through blood samples and sputum in Cystic Fibrosis (CF) population 1) Prospectively evaluating the pharmacokinetics and pharmacodynamics of colistin in adult CF patients infected by multidrug resistant P. aeruginosa in order to propose algorithms for optimizing doses...

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