Open, multicenter, randomised, controlled phase IIIb study evaluating the immunogenicity and safety of subcutaneous versus intramuscular administration of GlaxoSmithKline Biologicals’ combined measles-mumps-rubella-varicella vaccine (MeMuRu-OKA) to healthy children aged 11 to 21 months To evaluate GMT and seroconversion rate to VZV before and after intramuscular and subcutaneous injection of GSK’s MeMuRu-OKA vaccine.

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Wirkung der Bronchienerweiterung durch Salmeterol auf das autonome (sich selbst regulierende) Nervensystem The primary objective is to demonstrate a decrease in muscle sympathetic nerve activity (MSNA) evaluated by microneurography as bursts/100 heart beats after acute administration of salmeterol in COPD ...

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A 12-month open-label, randomized parallel-group study to investigate the influence of salmeterol/fluticasone either in fixed combination (SFC500/50 µg bid) or seperately (SAL 50 µg and FP 500 µg bid) via Diskus inhaler(s) on course of the disease and frequency of exacerbations in subjects with severe and very severe COPD (GOLD Stage III and IV) To obtain data on the frequency and variability of exacerbations in severe and very severe COPD patients (GOLD stage III und IV) receiving SFC or Sal/FP with individual standard therapy.

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A randomized, open-label, multicenter, parallel-group study to compare the efficacy, safety and resource utilization of a remifentanil/propofol analgosedation regimen versus a sufentanyl/propofol analgosedation regimen in ventilated patients under intensive medical care with an expected duration of analgosedation of up to 7 days Main objective of the study is the comparison of two regimes for analgesie and sedation (Remifentanil/Propofol vs. Sufentanil/Propofol) concerning the duration of artificial respiration and weaning.

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Reaching asthma control with salmeterol/fluticasone 50 / 250µg bd combination in steroid naive or low dose JCS patients by using the asthma control test (ACT) as measurement This study is intended to test whether symptomatic asthma patients receiving no inhaled corticosteroid or low-dosed inhaled corticosteroids will achieve “good” asthma control under treatment with the ...

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