TARGeted therapy using intradermal injection of ETanercept to treat Discoid Lupus Erythematosus (TARGET-DLE) To assess the proportion of patients with active discoid lupus erythematosus (DLE) that achieves a clinical response as assessed using the modified Limited Score of Activity and Damage in DLE (SADDLE)...

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Tocilizumab and Remission in early rheumatoid arthritis Tocilizumab (TCZ) is an anti-IL6 receptor monoclonal antibody. IL6 is a pro-inflammatory cytokine. Dyregulated production of this cytokine is implicated in the pathogenesis of rheumatoid arthritis (RA...

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Evidence-based information and communications technology tools for weight loss maintenance Background and study aims Obesity is a key economic and healthcare challenge for Europe. Most adults try to lose weight but fail to maintain it. Effective programmes for weight loss are widely availab...

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Does concentration affect the ED50 of bupivacaine for supraclavicular brachial plxus block? Does concentration affect the ED50 of 0.25%, 0.375% and 0.5% bupivacaine for supraclavicular brachial plexus block?

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Endocrine +/- Surgical Therapy for Elderly women with Mammary cancer Primary objective: To compare surgery plus Arimidex with Arimidex alone in older women with ER+ve breast cancer in terms of overall survival in order to determine whether Arimidex alone provides anti-...

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