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Kusajili – Clinical trials directory
Result
of your search per sponsor: F. Hoffmann-La Roche Ltd
Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
A single arm, open-label, phase II study of bevacizumab in combination with trastuzumab and capecitabine as first-line treatment of patients with HER2-positive locally recurrent or metastatic breast cancer
The primary objective is to evaluate the overall response rate (ORR) in patients with HER2-positive locally advanced or metastatic breast cancer receiving bevacizumab, trastuzumab and capecitabine as ...
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None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
Roche Farma, S.A., que representa en España a F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
A Study to Evaluate the Safety and Efficacy of Obinutuzumab, an antibody targeting certain types of immune cells, in Patients with Lupus Nephritis Estudio para evaluar la seguridad y eficacia de obinituzumab, un anticuerpo dirigido a determinado tipo de células inmunes, en pacientes son nefritis lúpica
? To evaluate the efficacy of obinutuzumab compared with placebo in patients with International Society of Nephrology (ISN)/Renal Pathology Society (RPS) Class III or IV Lupus Nephritis (LN) as measur...
Country
None
organs
None
Specialty
None
unknown
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Woman Max 99 years
F. Hoffmann-La Roche Ltd (Switzerland) - provided trastuzumab and financial support
Update Il y a 4 ans
Neoadjuvant trastuzumab in patients with HER2-positive locally advanced breast cancer
Not provided at time of registration
Country
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organs
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Specialty
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Closed trial
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
Randomized, blinded, controlled study to compare the efficacy of treatment with tocilizumab with or without glucocorticoids in rheumatoid arthritis
To compare the impact on disease activity of continued vs. tapered prednisone in RA patients with stable low disease activity (LDA [Disease Activity Score in 28 joints (DAS28) erythrocyte sedimentatio...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
A study comparing the clinical benefit and side effects of MPDL3280A to docetaxel in patients with lung cancer who have not benefited from platinum-containing cancer drugs
The primary objective of this study is to determine if MPDL3280A treatment results in superior OS compared with docetaxel treatment in patients with locally advanced or metastatic NSCLC who have progr...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
A multi-center, double-blind, randomized, placebo-controlled dose-ranging phase 2 study to investigate efficacy, safety, tolerability and pharmacokinetics of RO4389620 in patients with type 2 diabetes mellitus treated with a stable dose of metformin
To determine the BID dose(s) of RO4389620 administered in combination with metformin, which when compared to placebo (metformin monotherapy) are efficacious, safe and tolerable in improving glycemic c...
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
International study evaluating safety of Obinutuzumab alone or in combination with chemotherapy in patients with Chronic Lymphocytic Leukemia
• To evaluate the safety and tolerability of obinutuzumab alone or in combination with chemotherapy
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
A study of MDPL3280A in patients with advanced bladder cancer
Evaluated the efficacy of MPDL3280A in patients with locally advanced or metastatic urothelial bladder cancer as measured by independent review facility assessed ORR using RECIST v1.1 and investigator...
Country
None
organs
None
Specialty
None
unknown
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 4 ans
A Phase II, prospective, randomized, double-blind, active-controlled, parallel group, multi-center 'proof of concept' trial in adult patients with community-acquired pneumonia requiring hospitalization without evidence of Legionella
To compare the safety, tolerance and efficacy of parenteral RO4908463 to ceftriaxone in patients with community-acquired pneumonia requiring hospitalization without evidence of Legionella.
Country
None
organs
None
Specialty
None
Closed trial
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Woman and Man Max 99 years
F. Hoffmann-La Roche Ltd
Update Il y a 5 ans
A Study to Compare the Efficacy and Safety of Obinutuzumab + GDC-0199 versus Obinutuzumab + Chlorambucil in Patients with Chronic Lymphocytic Leukemia
To determine efficacy by investigator-assessed PFS of a combined regimen of obinutuzumab and Venetoclax compared with GClb in previously untreated patients with CLL who have coexisting medical conditi...
Country
None
organs
None
Specialty
None
unknown
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