A phase IV randomised, placebo controlled, double-blind, single centre, out-patient trial to investigate the functional benefit of botulinum toxin injections combined with physiotherapy treatment for spasticity of the upper limb after stroke To determine whether targeted injections of botulinum toxin combined with a standardised physiotherapy intervention improve functional grasp release time in stroke patients more than physiotherapy int...

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Multiple myeloma lifestyle study http://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-study-looking-at-lifestyle-after-treatment-for-myeloma

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VIP (Victim Improvement Package) Trial: helping older victims of crime with chronic symptoms of depression and or anxiety using a therapist delivered victim improvement package Background and study aims Being the victim of common crime can affect people deeply, with many going on to develop mental health issues such as depression and anxiety. The social and physical problems...

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Study of effectiveness of a smartphone app for stopping smoking focused on use of nicotine replacement therapy Background and study aims Nicotine replacement therapy (NRT) has been shown to be effective at helping people quit smoking in numerous clinical trials. However, the effectiveness of quit attempts wit...

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The EPICure2 Study: educational and health outcomes at 11 years of age following extremely preterm birth Background and study aims The national EPICure studies are concerned with the long term outcomes of babies who were born extremely premature (EP). EP births are only a small proportion of total births...

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A six weeks versus six months Study of oral valgancoclovir medicine and dummy medicine in infants with congenital cytomegalovirus infection symtoms To evaluate whether six months of antiviral treatment with oral valganciclovir improves hearing outcome in infants with symptomatic congenital CMV disease compared to six weeks.

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A Phase II Study to determine the efficacy and safety of conventional dose oral Treosulfan in patients with advanced pre-treated Ewing’s Sarcoma The main objective of this trial is to determine the effectiveness of oral treosulfan in patients with advanced pre-treated Ewing's Sarcoma.

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The HALT-LTBI Study To assess completion rates of two different LTBI treatment regimens (daily rifampicin/isoniazid, the current UK standard treatment, vs weekly rifapentine/isoniazid). The objective of the pilot phase...

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SIP SMART: Swallowing Intervention package - Self Monitoring, Assessment & Rehabilitation Training https://www.cancerresearchuk.org/about-cancer/find-a-clinical-trial/a-study-to-help-people-with-swallowing-after-treatment-for-head-and-neck-cancer

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RADAR Trial: Testing the effects of reducing and discontinuing antipsychotic medication in people with long-term schizophrenia and similar conditions Background and study aims Psychosis and schizophrenia are common and costly mental health problems. Psychosis is the name given to a group of mental conditions in which cause people to perceive or int...

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