A Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-centre, Dose Ranging Study to Evaluate the Efficacy and Safety of Losmapimod (GW856553) Tablets Administered Twice Daily compared ...

Mise à jour : Il y a 4 ans
Référence : EUCTR2010-019695-76

A Randomised, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-centre, Dose Ranging Study to Evaluate the Efficacy and Safety of Losmapimod (GW856553) Tablets Administered Twice Daily compared with Placebo for 24 Weeks in Adult Subjects with Chronic Obstructive Pulmonary Disease (COPD)

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Extrait

The objective of this study is to evaluate the efficacy, dose response, safety, tolerability and PK of three doses of losmapimod (2.5mg, 7.5mg and 15mg) administered twice daily compared with placebo in subjects with COPD. The study will evaluate primarily the effects of each dose on exercise tolerance, as assessed by the six-minute walk distance (6MWD).


Critère d'inclusion

  • Chronic Obstructive Pulmonary Disease (COPD)