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First trimester progesterone therapy to reduce miscarriages in women with a history of unexplained recurrent miscarriages: A randomised, double blind, placebo-controlled, multi-centre trial [The PROMI...

Mise à jour : Il y a 4 ans
Référence : EUCTR2009-011208-42

First trimester progesterone therapy to reduce miscarriages in women with a history of unexplained recurrent miscarriages: A randomised, double blind, placebo-controlled, multi-centre trial [The PROMISE (PROgesterone in recurretn MIScarriagE) Trial] Funded by NIHR-HTA(UK) 08/38/01 for ₤1.2 million

Femme Homme

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Extrait

PRINCIPAL OBJECTIVE: To test the hypothesis that in women with unexplained recurrent miscarriages, progesterone (400mg pessaries, twice daily), started as soon as possible after a positive pregnancy test (and no later than 6 weeks gestation) and continued to 12 weeks of gestation, compared to placebo, increases live births beyond 24 completed weeks by at least 10 %.

Critère d'inclusion

  • Recurrent Miscarriage

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