Extract

To report on the age-dependency of the effect(s) of the SSRI fluoxetine on the outgrowth of the serotonergic system using Magnetic Resonance Imaging (MRI) techniques

Inclusion criteria

• We investigate whether the effects fluoxetine (Prozac®) on the outgrowth of the serotonergic system are dependent on age. In a 16 week multicenter randomized, double-blind, placebo controlled trial with fluoxetine in 80 adolescents and adults suffering from MDD and/or anxiety, the effect of age is investigated using state of the art in vivo Magnetic Resonance Imaging (MRI) techniques that allow determination of the functional status of the 5-HT neurotransmitter system with pharmacological MRI

Links

• ictrp
• euctr