Clinical Trial testing TH-302 in combination with gemcitabine in combination in previously untreated patients with pancreatic cancer The primary objective of the trial is to evaluate efficacy, as measured by overall survival (OS), of gemcitabine in combination with TH-302 compared to gemcitabine in combination with placebo in subje...

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• Specialty None

A Randomized Phase 3 Study of the Efficacy and Safety of Glufosfamide Compared with Best Supportive Care in Metastatic Pancreatic Adenocarcinoma Previously Treated with Gemcitabine 1) To evaluate the efficacy of glufosfamide in subjects with metastatic pancreatic adenocarcinoma previously treated with gemcitabine as measured by overall survival compared with best supportive care...

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Study of TH-302 or Placebo in Combination With Pemetrexed in Patients With Advanced Non-Small Cell Lung Cancer Estudio con TH-302 o placebo en combinación con pemetrexed en pacientes con cáncer de pulmón no microcítico en fase avanzada To evaluate the efficacy of pemetrexed in combination with TH-302 as determined by overall survival (OS) in patients with advanced non-squamous NSCLC in the second-line chemotherapy setting compared w...

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A Randomised Phase 3, Double-Blind, Placebo-Controlled Study of the Efficacy and Safety of Lonidamine for the Treatment of Symptomatic Benign Prostatic Hyperplasia To evaluate the efficacy as measured by I-PSS of lonidamine (50 mg, 150 mg) compared to placebo in subjects with symptomatic BPH.

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SARC021 : Essai de phase 3, randomisé, visant à évaluer l’efficacité et la tolérance de l’association du TH-302 et de la doxorubicine par rapport à la doxorubicine seule, chez des patients ayant un sarcome des tissus mous, avancé ou métastatique. [Informations issues du site clinicaltrials.gov et traduites par l'INCa] [essai clos aux inclusions] L’objectif de cet essai est d’évaluer l’efficacité et la tolérance du TH-302 associé avec la doxorubicine, chez des patients ayant un sarcome des tissus mous, avancé ou métastatique. Les patients ser...

• Country France
• organs Sarcomes
• Specialty Thérapies Ciblées, Chimiothérapie