Investigation of the effect of E.-coli-Nissle as supporting therapy to antidiabetic standard care in patients with diabetes mellitus type 2 Untersuchung der Wirkung von E.-coli-Nissle als Unterstützung der Routinetherapie bei Patienten mit Diabetes Mellitus Typ 2 Decrease in HbA1c levels within baseline and end of treatment Senkung des HbA1c zwischen Baseline und End of treatment

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Therapy with Urokinase in patients with diabetic foot, non-healing wounds and pain in comparison to the standard therapy Lengthening of survival free of major amputation by a low dose therapy with Urokinase as a daily short infusion with 10 to 21 doses over max. 30 days within the scope of a randomized, controlled study

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Study to compare two gels that are used to treat acne vulgaris. It will be compared the tolerability and effectivity following application of two combination topical acne products clindamycin 1% and 0.025% tretinoin gel (Acnatac® Gel), adapalen 0,1% and benzoyl peroxide 2,5% gel (Epiduo® Gel). Studie zur Überprüfung, welches Gel zur Behandlung der Akne besser wirkt und verträglich ist. Verglichen werden Acnatac® Gel und Epiduo® Gel miteinander To compare the tolerability of the two acne products. The main variable ist the transepidermal water loss (TEWL) Vergleich der Verträglichkeit auf der Haut der beiden Akneprodukte. Hauptzielvari...

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MICROVASCULAR AND ANTIINFLAMMATORY EFFECTS OF RIVAROXABAN COMPARED TO ASPIRIN IN TYPE 2 DIABETIC PATIENTS WITH CARDIOVASCULAR RISK AND SUBCLINICAL INFLAMMATION Difference of change of forearm blood flow with venous occlusion plethysmography at baseline and after forearm ischemia after 20 weeks treatment between rivaroxoban and aspirin therapy. Additionally t...

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Intravenöse Eisencarboxymaltose-Applikation zur Verbesserung der metabolischen Parameter und der Gefäßfunktion bei Diabetes mellitus Typ 2-Patienten für 12 Wochen (Clever-Studie) reduction in HBA1c-levels between baseline and after 12 weeks of treatment with FCM vs. placebo

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RISK OF NOCTURNAL HYPOGLYCEMIA AND CRITICAL ARRHYTHMIAS WITH SITAGLIPTIN VERSUS GLIMEPIRIDE IN PATIENTS WITH TYPE 2 DIABETES Risikovergleich nächtlicher Hypoglykämie und kritischer Arrhythmien unter Einnahme von Sitagliptin gegenüber Glimepirid bei ungenügend kontrollierten Patienten mit Typ-2-Diabetes Hypoglycemic episodes (HE) and time spent below critical values are the primary objectives of this study. We will calculate overall episodes/time (5 days) and nocturnal episodes. Analysis will be p...

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Comparative investigation of Insuline glargine versus Metformin as first line drug in treat-ment of early Type 2 Diabetes (GLORY) To compare the treatment of an early Type II Diabetes mellitus with Insuline instead of the conventional treatment with Metformin. Evaluation of efficacy and safety of an early Diabetes mellitus Type ...

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Überprüfung einer ergänzenden Therapie des diabetischen Makulaödems mit dem Diodenlaser zur Standardtherapie mit VEGF-Inhibitoren To evaluate if a combination therapy with micropulse diode laser treatment shows non-inferiority on visual acuity within 12 months in comparison to standard therapy (intravitreal injection of ranibizu...

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