Fibrinogen concentrate to treat bleeding at the time of childbirth This study aims to establish whether giving fibrinogen (one of the body's blood clotting factors and it plays an important role is forming a strong clot) to women who are bleeding during childbirth an...

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Evidence into Practice: evaluating a Child-centred intervention for diabetes medicine management Not provided at time of registration

• Country None
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Randomised controlled trial of the effectiveness of a schools-based, peer-led, smoking intervention Not provided at time of registration

• Country United Kingdom
• organs None
• Specialty None

Leukaemia Lymphoma Research and NCRI Working Group Pick a Winner Programme (LI-1) Trial To compare standard treatment, low-dose Ara-C against the available novel approaches: •LD Ara-C combined with AC220 •LD Ara-C combined with Ganetespib •LD Ara-C combined with Tosedostat •LD Ara...

• Country None
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A multi-centre randomised phase II study of induction chemotherapy followed by gemcitabine or capecitabine based chemoradiotherapy (CRT) for locally advanced non-metastatic pancreatic cancer To evaluate the activity, safety and feasibility of two chemoradiation treatments in the management of LANPC. If either is found to be active, safe and feasible to use it may be considered as experime...

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A randomised, double blind, placebo-controlled study of RAD001 (Everolimus) in the treatment of neurocognitive problems in tuberous sclerosis Background and study aims Tuberous sclerosis (TSC) is a genetic disorder affecting approximately 1 in 10,000 people. It is characterised by the development of tumours in many organs and can lead to se...

• Country None
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Gamma Delta T Cells and their role in the acute phase reaction to intravenous bisphosphonates to determine whether the presence acute phase reaction to aminobisphosphonates can be predicted by exanination of the gamma delta T cells of a patient

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Children with eczema, antibiotic management study Background and study aims Eczema is a common, debilitating skin condition in children that causes dryness and itching. Everyone naturally has bacteria on their skin, though one called Staphylococcus ...

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The AML19 Trial is an intensive chemotherapy trial for patients between 18 and 60 with AML and High Risk Myelodysplastic disease The AML19 trial looks to build upon previous trials in AML. It is known that the condition can present with one of two subtypes, and this is taken into account in the trial design. In the majority...

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Adapting and piloting the ASSIST model of informal peer-led intervention delivery to the Talk to Frank drug prevention programme in UK secondary schools (ASSIST+Frank) Background and study aims Reducing youth drug use is a public health priority. There is no way of identifying people who are likely to graduate from experimenting with drugs to long-term drug use. A...

• Country None
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• Specialty None