LEO19123 Cream in the Treatment of Hand Eczema A Phase II, proof of concept study, testing once daily use of two dose-combinations of LEO19123 cream (calcipotriol and LEO80122) in the treatment of hand eczema To compare the clinical efficacy of LEO19123 cream (calcipotriol 50 mcg/g and LEO80122 0.6 mg/g), LEO19123 cream (calcipotriol 15 mcg/g and LEO80122 0.2 mg/g), and LEO19123 cream vehicle alone, in pat...

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Calcipotriol plus Betamethasone Dipropionate Gel Compared to Calcipotriol in the Gel Vehicle and Betamethasone Dipropionate in the Gel Vehicle in Scalp Psoriasis. A phase III study comparing a gel containing calcipotriol 50 mcg/g plus betamethasone dipropionate 0.5 mg/g (as dipropionate) with calcipotriol 50 mcg/g in the gel vehicle and betamethasone 0.5 mg/g (as dipropionate) in the gel vehicle, all applied once daily in the treatment of scalp psoriasis To compare the clinical efficacy of once daily treatment for up to 8 weeks of calcipotriol plus betamethasone dipropionate gel with betamethasone dipropionate in the gel vehicle, and calcipotriol in t...

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LEO19123 Cream in the Treatment of Atopic Dermatitis A Phase II, proof of concept study, testing once daily use of two dose-combinations of LEO19123 cream (calcipotriol and LEO80122) in the treatment of atopic dermatitis To compare the clinical efficacy of LEO19123 cream (calcipotriol 50 mcg/g and LEO80122 0.6 mg/g), LEO19123 cream (calcipotriol 15 mcg/g and LEO80122 0.2 mg/g), and LEO19123 cream vehicle alone, in pat...

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A Simultaneous Treatment Regimen Compared to a Sequential Treatment Regimen with Ingenol Mebutate Gel 0.015% and 0.05% of Two Areas with Actinic Keratosis on Face/Scalp and Trunk/Extremities Un regime di trattamento simultaneo comparato ad un regime di trattamento sequenziale con Ingenolo mebutato Gel allo 0.015% e 0.05% di due aree con cheratosi attinica su Viso/Cuoio cappelluto e Tronco/Estremità To evaluate the safety of a simultaneous treatment regimen compared to a sequential treatment regimen when two separate areas with AKs (one located on face or scalp and the other located on trunk or...

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A phase 2a proof of concept study comparing three doses of an oral solution of LEO 22811 with a placebo oral solution for the treatment of psoriasis vulgaris To compare the clinical efficacy of three different doses (0.5 mg, 1.5 mg and 3.0 mg) of an oral solution of LEO 22811 with a placebo oral solution all administered once daily for up to 12 weeks in su...

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A research study to evaluate the efficacy of LEO 32731 oral tablet formulation in patients with moderate to severe psoriasis vulgaris To investigate the efficacy of LEO 32731 30 mg as compared to placebo after 16 weeks of oral treatment of psoriasis vulgaris.

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Incidence of squamous cell carcinoma and other skin neoplasia in subjects with actinic keratosis (sun spots) treated with ingenol disoxate gel or vehicle Incidencia del carcinoma de células escamosas y otras neoplasias de la piel en pacientes con queratosis actínicas (manchas solares) tratados ingenol disoxato gel o placebo To compare the incidence of squamous cell carcinoma after treatment with ingenol disoxate gel and vehicle gel Comparar la incidencia del carcinoma de células escamosas tras el tratamiento con ge...

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A plaque test comparing three marketed products and two products in development and a vehicle control for the treatment of psoriasis vulgaris To evaluate a psoriasis plaque test using two (2) investigational products LEO 80185 gel and LEO 80190 ointment and three (3) active marketed reference products Daivobet® ointment, Daivonex® ointment,...

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A psoriasis plaque test trial with LEO 90100 compared to Betesil® in patients with psoriasis vulgaris To evaluate the anti-psoriatic effect of LEO 90100 aerosol foam compared with Betesil® medicated plaster.

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Effect of Calcipotriol Plus Hydrocortisone Ointment on the HPA Axis and Calcium Metabolism in Patients with Psoriasis Vulgaris on the Face and on the Intertriginous Areas To evaluate the effect of once daily use of calcipotriol 25 mcg/g plus hydrocortisone 10 mg/g ointment on the hypothalamic-pituitary-adrenal (HPA) axis in patients with psoriasis vulgaris on the face ...

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