Clinical study for patients with breast cancer that has spread to other parts of the body and that does not respond to hormonal or anti-HER2 therapy ('triple negative disease'), comparing a chemotherapy treatment (carboplatin + gemcitabine) with an experimental treatment of nab-paclitaxel plus chemotherapy (carboplatin OR gemcitabine) - Phase 2: evaluate the benefit and risk profiles of the two nab-paclitaxel experimental arms and identify the nab-paclitaxel combination that will be used in the Phase 3. - Phase 3: compare the p...

• Country None
• organs None
• Specialty None

A clinical trial to compare the safety and effectiveness of Abraxane versus dacarbazine, in the treatment of advanced stage melanoma that has spread to other parts of the body (metastatic malignant melanoma) The primary objective of this study is to compare the following regimens with respect to antitumor activity in patients who are previously untreated with cytotoxic chemotherapy for metastatic malignan...

• Country None
• organs None
• Specialty None

Essai de phase 3 randomisé comparant l’efficacité et la tolérance de l’ABI-007 à la dacarbazine, chez des patients ayant un mélanome métastatique. [essai clos aux inclusions] L’objectif de cet essai est de comparer l’efficacité et la tolérance de l’ABI-007 à la dacarbazine, chez des patients ayant un mélanome métastatique. Les patients seront répartis de façon aléatoire e...

• Country France
• organs Mélanomes cutanés
• Specialty Chimiothérapie