Woman and Man
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Extract
a. In elderly patients (≥ 65 years old) who are clinically evaluable, to assess the efficacy of ertapenem with respect to high-dose levofloxacin measured as the proportion of patients achieving a favorable clinical response (“cure”) at (a) DOT, and (b) 2 weeks post-DOT (TOC). b. Using serial rectal swabs obtained from patients enrolled in the study who are being treated for CAP, to assess the impact of therapy with ertapenem versus high-dose levofloxacin on the emergence of resistant gram-negative microorganisms in the bowel flora.
Inclusion criteria
- Community Acquired Bacterial Pneumonia with criteria of seriousness and great likelihood of polymicrobial or gram-negative microbial etiology