Woman and Man
- | Country :
- France
- | organs : -
- | Specialty : -
Extract
This study intends to optimize a fluorouracil/irinotecan chemotherapy regimen by the identification of individual thymidylate synthase (TS) and UDP-glucuronosyltransferase 1 (UGT1A1) polymorphisms before the first administration. The results of this identification determine the chemotherapy type: high-dose irinotecan or not.
Inclusion criteria
- Metastatic colorectal cancer