Eyelid measurements using Optical Coherence Tomography (OCT) scanning

A novel approach of eyelid measurements using swept-source anterior segment Optical Coherence Tomography

Registry ID
ISRCTN13849672
Source registry
ISRCTN
Status
Recruiting
Study type
OBSERVATIONAL
Sponsor
Northern Care Alliance NHS Foundation Trust
Enrollment
50
Start date
2026-05-13
Completion date
2026-11-09
Last update
2026-08-17

Conditions

Summary

Eyelid measurements

Detailed description

Participants will be recruited and assessed during the Oculoplastics Outpatient clinics Participants who fulfil the inclusion criteria will be consented by the research team on the day, they will undergo the additional Anterion OCT scanning measurements of their eyelids in both eyes as patients have their eyelid measurements clinically as a routine practice in the clinic. The Anterior Heidelberg Engineering OCT scanner, which is already in use in outpatient Opthahlmology clinics will be utilised. Furthermore, a digital camera will be used for the photographs. The equipment for the clinical measurements which includes a pen torch, and a ruler are already in place in clinics. Therefore, no additional equipment or additional specific requirements are needed. The order of the measurements will be random to avoid any order effect. A sample of 50 participants will be used which is desirable for a method comparison study. The accuracy of the measurements of the Anterion-OCT scan of the palpebral aperture and MRD1 compared to standard clinical measurement and digital photography and assess inter-method reliability will be validated. Furthermore, a review of any other possible useful measurements in the OCT scans will be performed.

Interventions

Inclusion criteria

1. Adults (≥18 years) with normal eyelid anatomy, diagnosed ptosis, eyelid retraction or globe proptosis 2. Ability to provide informed consent

Exclusion criteria

1. Patients with brow ptosis or other condition that can affect the eyelid position except for ptosis 2. Patients with severe ptosis covering the central pupil 3. Patients with severe proptosis 4. Patients with severe upper or lower lid retraction 5. Patients with entropion, ectropion or eyelid lesions 6. History of previous eyelid or periocular surgery in the past 6 months 7. Patients unable to comply with imaging protocols 8. Patients who lack capacity to consent for themselves

Locations

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