NeuroMooD – Neurofeedback in depression Background and study aims Depression is one of the most common mental disorders worldwide. The symptoms of depression can vary greatly from person to person, but generally include low mood, problems w...

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Effect of experimental endocannabinoid modulation on brain function in individuals at high risk for psychosis Background and study aims The human body has an internal system known as the endocannabinoid system which regulates processes within the body. The purpose of this study is to find out how the endocann...

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Naltrexone Enhanced Addiction Treatment (NEAT): A randomised controlled trial of the clinical and cost-effectiveness of extended-release naltrexone and oral naltrexone A. Is XR-NTX treatment more effective than placebo at reducing heroin use? B. Is XR-NTX more effective than O-NTX at reducing heroin use? C. Is XR-NTX more cost- effective than placebo in terms of q...

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Wall thickness in the upper chamber of the heart and its effect on heart rhythm disorders Background and study aims Atrial fibrillation (AF) is a common heart condition affecting around 2% of the UK population. When a patient suffers from AF the atria (upper chambers in their heart) stop p...

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This a study using Atomoxetine in children with Attention Deficit Hyperactivity Disorder (ADHD) and a specific deletion in the 22qDS gene What is the efficacy of atomoxetine in reducing the symptoms of ADHD among children with 22qDS who also have ADHD.

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Can we prevent Crohn's disease: a National study Not provided at time of registration

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MODIFY Fatigue: a cognitive-behavioral therapy intervention study to improve fatigue in inflammatory bowel disease patients Background and study aims Inflammatory bowel disease (IBD) is a term used to describe conditions which cause long-term inflammation (swelling) in the gut. The two main forms of IBD are Crohn’s disease...

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Evaluation of the efficacy of colchicine with and without betamethasone mouthwash in the management of recurrent aphthous stomatitis To assess the efficacy of topical steroid and Colchicine, individually and combined, in the treatment of RAS.

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COST and cost-effectiveness of models of care for children with Eating Disorders (CostED) Background and study aims Anorexia nervosa is a serious mental health problem that can last for many years and carries a high risk of death from malnutrition. It is harmful for those affected and can...

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Repetitive transcranial magnetic stimulation (rTMS) and neuroimaging in anorexia nervosa Background and study aims Anorexia nervosa (AN) is a disabling and deadly disorder. After about 3-5 years, AN can be considered as enduring and difficult to change. Most adults with AN have an enduri...

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